Euclid Avenue is a major street in Cleveland, Ohio. It runs northeasterly from the Public Square in Downtown Cleveland, through the cities of East Cleveland, Euclid and Wickliffe, to the suburb of Willoughby as a part of U.S. Route 20 and U.S. Route 6. The street passes Playhouse Square, the University Circle, Cleveland State University, the Cleveland Clinic, Severance Hall, Tifereth Israel (The Temple), Case Western Reserve University andUniversity Hospitals Case Medical Center. The HealthLine bus rapid transit line runs in designated bus lanes in the median of Euclid Avenue from Public Square to Louis Stokes Station at Windermere in East Cleveland.
It received nationwide attention from the 1860s to the 1920s for its beauty and wealth, including a string of mansions that came to be known as Millionaires' Row. There are several theaters, banks, and churches along Euclid, as well as Cleveland's oldest extant building, the Dunham Tavern. A large reconstruction project, which brought a bus rapid transit line to the street, was completed in 2008.